Theses

THESIS OF MASTER’S DEGREE IN BIOMEDICAL ENGINEERING

Long-term variability of airway obstructions in asthma and the influence of air pollution

The aim of this work was to analyze the forced oscillations (FOT) data recorded during a previous clinical trial in which ten healthy and ten asthmatic individuals recorded daily their respiratory parameters, in order to explore with more detail the long-term variability and the complexity in the respiratory system and how the consequent long temporal variability can be connected by an external stimulus as the air pollution.

The results were also the theme of an abstract sent to “European Respiratory Society Annual Congress 2012 – Poster Discussion that was held in Vienna (A) in September 2012 and published in European Respiratory journal, September 1, 2011 vol. 38 no. Suppl 55 p928 and European Respiratory journal, September 1, 2012 vol. 40 no. Suppl 56 p4784

 

THESIS OF BACHELOR’S DEGREE IN BIOMEDICAL ENGINEERING

Extraction of quantitative indexes for the evaluation of the electromyographic activity in hemiparetic patients

The aim of this study was the extraction of parameters which allowed the estimation of the Electromiographic activity in hemiparetic patients.

After a study of literature about elettromiographic analysis during pedaling, tests were conducted on six healthy subjects in order to detect the muscles activation timing. With these tests it could be possible to assess the motor strategy used by healthy subjects and to estimate parameters able to evaluate the fluency of movement (RI), the symmetry of EMG activation and the phase-displacement between the legs (SA).

Finally these parameters were evaluated during tests of cycling movement executed by poststroke patients.

The conclusions were these:

  • the RI index marked out the healthy subjects from the hemiparetic subjects in the best way;
  • the SI index could be used only with the most serious patients;
  • the SA index was usable only with the graphic evaluation of the EMG timing.

In the future these parameters will be used in order to evaluate the efficiency of a treatment of cycling induced by functional electrical stimulation of individuals with post-acute stroke. In fact, among the biomechanical tests of evaluation, a test of voluntary cycling (performed during pre-treatment, post-treatment and 3/5 months after the end of treatment) was been included.

These indexes could be used in order to obtain both an intrasubjective analysis of the motor recovery of each patients and an intersubjective analysis among both patients who performed this innovative treatment and those who perfomed a placebo treatment.